Zinc Finger Protein 451 Is a Novel Smad Corepressor in Transforming Growth Factor-β Signaling

ZNF451 is a transcriptional cofactor localized to promyelocytic leukemia bodies. Here, we present evidence demonstrating that ZNF451 physically interacts with Smad3/4 and functionally inhibits TGF-β signaling. Increased expression of ZNF451 attenuates TGF-β-induced growth inhibitory and gene transcr...

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Detaylı Bibliyografya
Asıl Yazarlar: Feng, Yili, Wu, Hongxing, Xu, Yongxian, Zhang, Zhengmao, Liu, Ting, Lin, Xia, Feng, Xin-Hua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900955/
https://ncbi.nlm.nih.gov/pubmed/24324267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.526905
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