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Transforming Growth Factor β Can Stimulate Smad1 Phosphorylation Independently of Bone Morphogenic Protein Receptors
Transforming growth factor-β (TGFβ) superfamily ligands control a diverse set of cellular processes by activating type I and type II serine-threonine receptor kinases. Canonical TGFβ signaling is mediated via the TβRI/ALK5 type I receptor that phosphorylates Smad2 and Smad3 in their SXS motif to fac...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665096/ https://ncbi.nlm.nih.gov/pubmed/19224917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809223200 |
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