Transforming Growth Factor-β-inducible Phosphorylation of Smad3

Smad proteins transduce the transforming growth factor-β (TGF-β) signal at the cell surface into gene regulation in the nucleus. Upon TGF-β treatment, the highly homologous Smad2 and Smad3 are phosphorylated by the TGF-β receptor at the SSXS motif in the C-terminal tail. Here we show that in additio...

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Bibliographic Details
Main Authors: Wang, Guannan, Matsuura, Isao, He, Dongming, Liu, Fang
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665087/
https://ncbi.nlm.nih.gov/pubmed/19218245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809281200
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