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Epigenetic changes during hematopoietic cell granulocytic differentiation – comparative analysis of primary CD34+ cells, KG1 myeloid cells and mature neutrophils

BACKGROUND: Epigenetic regulation is known to affect gene expression, and recent research shows that aberrant DNA methylation patterning and histone modifications may play a role in leukemogenesis. In order to highlight the co-operation of epigenetic mechanisms acting during the latter process it is...

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Main Authors: Navakauskienė, Rūta, Borutinskaitė, Veronika V, Treigytė, Gražina, Savickienė, Jūratė, Matuzevičius, Dalius, Navakauskas, Dalius, Magnusson, Karl-Eric
格式: Artigo
語言:Inglês
出版: BioMed Central 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900736/
https://ncbi.nlm.nih.gov/pubmed/24443786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-15-4
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