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Enigma Prevents Cbl-c-Mediated Ubiquitination and Degradation of RETMEN2A
The Cbl proteins (Cbl, Cbl-b, and Cbl-c) are a highly conserved family of RING finger ubiquitin ligases (E3s) that function as negative regulators of tyrosine kinases in a wide variety of signal transduction pathways. In this study, we identify a new Cbl-c interacting protein, Enigma (PDLIM7). This...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900716/ https://ncbi.nlm.nih.gov/pubmed/24466333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087116 |
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