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B Cell-Specific Loss of Lyn Kinase Leads to Autoimmunity
The Lyn tyrosine kinase regulates inhibitory signaling in B and myeloid cells – loss of Lyn results in a lupus-like autoimmune disease with hyperactive B cells and myeloproliferation. We have characterized the relative contribution of Lyn-regulated signaling pathways in B cells specifically to the d...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900234/ https://ncbi.nlm.nih.gov/pubmed/24376269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301979 |
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