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Clinical Pharmacokinetics of Clopidogrel and Its Metabolites in Patients with Cardiovascular Diseases

BACKGROUND AND OBJECTIVE: Approximately 5–40 % of patients treated with clopidogrel do not display an adequate antiplatelet response. Clopidogrel resistance may be caused by insufficient drug absorption or impaired metabolic activation of the drug. The aim of this study was to evaluate the pharmacok...

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Main Authors: Karaźniewicz-Łada, Marta, Danielak, Dorota, Burchardt, Paweł, Kruszyna, Łukasz, Komosa, Anna, Lesiak, Maciej, Główka, Franciszek
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899497/
https://ncbi.nlm.nih.gov/pubmed/24127209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-013-0105-2
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