Clinical Pharmacokinetics of Clopidogrel and Its Metabolites in Patients with Cardiovascular Diseases

BACKGROUND AND OBJECTIVE: Approximately 5–40 % of patients treated with clopidogrel do not display an adequate antiplatelet response. Clopidogrel resistance may be caused by insufficient drug absorption or impaired metabolic activation of the drug. The aim of this study was to evaluate the pharmacok...

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Hlavní autoři: Karaźniewicz-Łada, Marta, Danielak, Dorota, Burchardt, Paweł, Kruszyna, Łukasz, Komosa, Anna, Lesiak, Maciej, Główka, Franciszek
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2013
Témata:
Original Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899497/
https://ncbi.nlm.nih.gov/pubmed/24127209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-013-0105-2
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