Loss of the proteins Bak and Bax prevents apoptosis mediated by histone deacetylase inhibitors

Burkitt lymphoma is characterized by deregulation of c-myc, and therapies targeting c-myc are under investigation as treatments. Histone deacetylase inhibitors are known to abrogate c-myc expression, leading us to examine their effect in a series of Burkitt lymphoma cell lines. While treatment with...

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Bibliographic Details
Main Authors: Ierano, Caterina, Chakraborty, Arup R, Nicolae, Alina, Bahr, Julian C, Zhan, Zhirong, Pittaluga, Stefania, Bates, Susan E, Robey, Robert W
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899196/
https://ncbi.nlm.nih.gov/pubmed/23966164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25914
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