Investigation of Complement Component C4 Copy Number Variation in Human Longevity

Genetic factors have been estimated to account for about 25% of the variation in an adult's life span. The complement component C4 with the isotypes C4A and C4B is an effector protein of the immune system, and differences in the overall C4 copy number or gene size (long C4L; short C4S) may infl...

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Detaylı Bibliyografya
Asıl Yazarlar: Flachsbart, Friederike, Caliebe, Amke, Heinsen, Femke-Anouska, Hemming-Karlsen, Tom, Schreiber, Stefan, Franke, Andre, Nebel, Almut
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899116/
https://ncbi.nlm.nih.gov/pubmed/24465950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086188
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