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Depletion of potential A2M risk haplotype for Alzheimer's disease in long-lived individuals
Risk alleles for age-related diseases are expected to decrease in frequency in the population strata of increasing age. Consistent with this hypothesis, earlier studies showed a depletion of the Alzheimer's disease risk factor APOE(*)ɛ4 in long-lived individuals (LLIs). To evaluate whether this...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987169/ https://ncbi.nlm.nih.gov/pubmed/19639019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.136 |
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