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Association of FOXO3A variation with human longevity confirmed in German centenarians

The human forkhead box O3A gene (FOXO3A) encodes an evolutionarily conserved key regulator of the insulin–IGF1 signaling pathway that is known to influence metabolism and lifespan in model organisms. A recent study described 3 SNPs in the FOXO3A gene that were statistically significantly associated...

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Bibliografische gegevens
Hoofdauteurs: Flachsbart, Friederike, Caliebe, Amke, Kleindorp, Rabea, Blanché, Hélène, von Eller-Eberstein, Huberta, Nikolaus, Susanna, Schreiber, Stefan, Nebel, Almut
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650329/
https://ncbi.nlm.nih.gov/pubmed/19196970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809594106
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