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Association of FOXO3A variation with human longevity confirmed in German centenarians
The human forkhead box O3A gene (FOXO3A) encodes an evolutionarily conserved key regulator of the insulin–IGF1 signaling pathway that is known to influence metabolism and lifespan in model organisms. A recent study described 3 SNPs in the FOXO3A gene that were statistically significantly associated...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650329/ https://ncbi.nlm.nih.gov/pubmed/19196970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809594106 |
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