Immunochip analysis identifies association of the RAD50/IL13 region with human longevity

Human longevity is characterized by a remarkable lack of confirmed genetic associations. Here, we report on the identification of a novel locus for longevity in the RAD50/IL13 region on chromosome 5q31.1 using a combined European sample of 3208 long‐lived individuals (LLI) and 8919 younger controls....

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Vydáno v:Aging Cell
Hlavní autoři: Flachsbart, Friederike, Ellinghaus, David, Gentschew, Liljana, Heinsen, Femke‐Anouska, Caliebe, Amke, Christiansen, Lene, Nygaard, Marianne, Christensen, Kaare, Blanché, Hélène, Deleuze, Jean‐François, Derbois, Céline, Galan, Pilar, Büning, Carsten, Brand, Stephan, Peters, Anette, Strauch, Konstantin, Müller‐Nurasyid, Martina, Hoffmann, Per, Nöthen, Markus M., Lieb, Wolfgang, Franke, Andre, Schreiber, Stefan, Nebel, Almut
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854908/
https://ncbi.nlm.nih.gov/pubmed/27004735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12471
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