Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity

Eukaryotic protein kinases are generally classified as being either tyrosine or serine-threonine specific. Though not evident from inspection of their primary sequences, many serine-threonine kinases display a significant preference for serine or threonine as the phosphoacceptor residue. Here we sho...

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Detalhes bibliográficos
Main Authors: Chen, Catherine, Ha, Byung Hak, Thévenin, Anastasia F., Lou, Hua Jane, Zhang, Rong, Yip, Kevin Y., Peterson, Jeffrey R., Gerstein, Mark, Kim, Philip M., Filippakopoulos, Panagis, Knapp, Stefan, Boggon, Titus J., Turk, Benjamin E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2014
Assuntos:
Short Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898841/
https://ncbi.nlm.nih.gov/pubmed/24374310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.11.013
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