Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity

Eukaryotic protein kinases are generally classified as being either tyrosine or serine-threonine specific. Though not evident from inspection of their primary sequences, many serine-threonine kinases display a significant preference for serine or threonine as the phosphoacceptor residue. Here we sho...

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Autores principales: Chen, Catherine, Ha, Byung Hak, Thévenin, Anastasia F., Lou, Hua Jane, Zhang, Rong, Yip, Kevin Y., Peterson, Jeffrey R., Gerstein, Mark, Kim, Philip M., Filippakopoulos, Panagis, Knapp, Stefan, Boggon, Titus J., Turk, Benjamin E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2014
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Short Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898841/
https://ncbi.nlm.nih.gov/pubmed/24374310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.11.013
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