TLR4 signaling is essential for survival in acute lung injury induced by virulent Pseudomonas aeruginosa secreting type III secretory toxins

BACKGROUND: The relative contributions of the cytotoxic phenotype of P. aeruginosa expressing type III secretory toxins and an immunocompromised condition lacking normal Toll-like receptor 4 (TLR4) signaling in the pathogenesis of acute lung injury and sepsis were evaluated in a mouse model for Pseu...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Faure, Karine, Sawa, Teiji, Ajayi, Temitayo, Fujimoto, Junichi, Moriyama, Kiyoshi, Shime, Nobuaki, Wiener-Kronish, Jeanine P
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2004
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389879/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15040820/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1465-9921-5-1
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