TLR4 signaling is essential for survival in acute lung injury induced by virulent Pseudomonas aeruginosa secreting type III secretory toxins

BACKGROUND: The relative contributions of the cytotoxic phenotype of P. aeruginosa expressing type III secretory toxins and an immunocompromised condition lacking normal Toll-like receptor 4 (TLR4) signaling in the pathogenesis of acute lung injury and sepsis were evaluated in a mouse model for Pseu...

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Main Authors: Faure, Karine, Sawa, Teiji, Ajayi, Temitayo, Fujimoto, Junichi, Moriyama, Kiyoshi, Shime, Nobuaki, Wiener-Kronish, Jeanine P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC389879/
https://ncbi.nlm.nih.gov/pubmed/15040820
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