Effects of monoclonal anti-PcrV antibody on Pseudomonas aeruginosa-induced acute lung injury in a rat model

BACKGROUND: The effects of the murine monoclonal anti-PcrV antibody Mab166 on acute lung injury induced by Pseudomonas aeruginosa were analyzed in a rat model. METHODS: Lung injury was induced by the instillation of P. aeruginosa strain PA103 directly into the left lungs of anesthetized rats. One ho...

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Autori principali: Faure, Karine, Fujimoto, Junichi, Shimabukuro, David W, Ajayi, Temitayo, Shime, Nobuaki, Moriyama, Kiyoshi, Spack, Edward G, Wiener-Kronish, Jeanine P, Sawa, Teiji
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2003
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC194171/
https://ncbi.nlm.nih.gov/pubmed/12943554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-8518-1-2
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