Role of Alveolar Macrophages in Initiation and Regulation of Inflammation in Pseudomonas aeruginosa Pneumonia

To evaluate the role of alveolar macrophages (AMs) in acute Pseudomonas aeruginosa pneumonia in mice, AMs were depleted by aerosol inhalation of liposomes containing clodronate disodium. AM-depleted mice were then intratracheally infected with 5 × 10(5) CFU of P. aeruginosa. In addition to monitorin...

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Detalhes bibliográficos
Main Authors: Kooguchi, Kunihiko, Hashimoto, Satoru, Kobayashi, Atsuko, Kitamura, Yoshihiro, Kudoh, Ichidai, Wiener-Kronish, Jeanine, Sawa, Teiji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108328/
https://ncbi.nlm.nih.gov/pubmed/9632581
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