Role of Alveolar Macrophages in Initiation and Regulation of Inflammation in Pseudomonas aeruginosa Pneumonia

To evaluate the role of alveolar macrophages (AMs) in acute Pseudomonas aeruginosa pneumonia in mice, AMs were depleted by aerosol inhalation of liposomes containing clodronate disodium. AM-depleted mice were then intratracheally infected with 5 × 10(5) CFU of P. aeruginosa. In addition to monitorin...

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Bibliographic Details
Main Authors: Kooguchi, Kunihiko, Hashimoto, Satoru, Kobayashi, Atsuko, Kitamura, Yoshihiro, Kudoh, Ichidai, Wiener-Kronish, Jeanine, Sawa, Teiji
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC108328/
https://ncbi.nlm.nih.gov/pubmed/9632581
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