TLR4 signaling is essential for survival in acute lung injury induced by virulent Pseudomonas aeruginosa secreting type III secretory toxins

BACKGROUND: The relative contributions of the cytotoxic phenotype of P. aeruginosa expressing type III secretory toxins and an immunocompromised condition lacking normal Toll-like receptor 4 (TLR4) signaling in the pathogenesis of acute lung injury and sepsis were evaluated in a mouse model for Pseu...

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Veröffentlicht in:	Respir Res
Hauptverfasser:	Faure, Karine, Sawa, Teiji, Ajayi, Temitayo, Fujimoto, Junichi, Moriyama, Kiyoshi, Shime, Nobuaki, Wiener-Kronish, Jeanine P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2004
Schlagworte:	Research
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15040820/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1465-9921-5-1
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