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Spindle Formation in the Mouse Embryo Requires Plk4 in the Absence of Centrioles
During the first five rounds of cell division in the mouse embryo, spindles assemble in the absence of centrioles. Spindle formation initiates around chromosomes, but the microtubule nucleating process remains unclear. Here we demonstrate that Plk4, a protein kinase known as a master regulator of ce...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cell Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3898710/ https://ncbi.nlm.nih.gov/pubmed/24268700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.09.029 |
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