Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes

Establishing the bipolar spindle in mammalian oocytes after their prolonged arrest is crucial for meiotic fidelity and subsequent development. In contrast to somatic cells, the first meiotic spindle assembles in the absence of centriole-containing centrosomes. Ran-GTP can promote microtubule nucleat...

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Bibliografische gegevens
Gepubliceerd in:J Cell Biol
Hoofdauteurs: Bury, Leah, Coelho, Paula A., Simeone, Angela, Ferries, Samantha, Eyers, Claire E., Eyers, Patrick A., Zernicka-Goetz, Magdalena, Glover, David M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674873/
https://ncbi.nlm.nih.gov/pubmed/28972102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201606077
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