Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes

Establishing the bipolar spindle in mammalian oocytes after their prolonged arrest is crucial for meiotic fidelity and subsequent development. In contrast to somatic cells, the first meiotic spindle assembles in the absence of centriole-containing centrosomes. Ran-GTP can promote microtubule nucleat...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Bury, Leah, Coelho, Paula A., Simeone, Angela, Ferries, Samantha, Eyers, Claire E., Eyers, Patrick A., Zernicka-Goetz, Magdalena, Glover, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674873/
https://ncbi.nlm.nih.gov/pubmed/28972102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201606077
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