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Tissue specific requirement of Drosophila Rcd4 for centriole duplication and ciliogenesis

Rcd4 is a poorly characterized Drosophila centriole component whose mammalian counterpart, PPP1R35, is suggested to function in centriole elongation and conversion to centrosomes. Here, we show that rcd4 mutants exhibit fewer centrioles, aberrant mitoses, and reduced basal bodies in sensory organs....

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Panda, Pallavi, Kovacs, Levente, Dzhindzhev, Nikola, Fatalska, Agnieszka, Persico, Veronica, Geymonat, Marco, Riparbelli, Maria Giovanna, Callaini, Giuliano, Glover, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401805/
https://ncbi.nlm.nih.gov/pubmed/32543652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201912154
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