Nr4a1-Dependent Ly6C(low) Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

The functions of Nr4a1-dependent Ly6C(low) monocytes remain enigmatic. We show that they are enriched within capillaries and scavenge microparticles from their lumenal side in a steady state. In the kidney cortex, perturbation of homeostasis by a TLR7-dependent nucleic acid “danger” signal, which ma...

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Detalhes bibliográficos
Main Authors: Carlin, Leo M., Stamatiades, Efstathios G., Auffray, Cedric, Hanna, Richard N., Glover, Leanne, Vizcay-Barrena, Gema, Hedrick, Catherine C., Cook, H. Terence, Diebold, Sandra, Geissmann, Frederic
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898614/
https://ncbi.nlm.nih.gov/pubmed/23582326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.03.010
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