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The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and survival of Ly6C(−) monocytes
Transcription factors that regulate monocyte subset differentiation in bone marrow have not yet been identified. Here we show that the orphan nuclear receptor NR4A1 controls Ly6C(−) monocyte differentiation. Ly6C(−) monocytes , which function in a surveillance role in circulation, were absent in Nr4...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324395/ https://ncbi.nlm.nih.gov/pubmed/21725321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2063 |
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