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Genetics of Myeloproliferative Neoplasms
In the last decade, genomic studies have identified multiple recurrent somatic mutations in myeloproliferative neoplasms. Beginning with the discovery of the JAK2 V617F mutation, multiple additional mutations have been found which constitutively activate cell-signaling pathways, including MPL, CBL,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3898518/ https://ncbi.nlm.nih.gov/pubmed/24445766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000013 |
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