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Epigenetic Dysregulation of Myeloproliferative Neoplasms

Genetic discovery studies have revealed the genomic heterogeneity of myeloproliferative neoplasms (MPN) with respect to mutations beyond the canonical driver genes JAK2, calreticulin (CALR), and MPL. Mutations in epigenetic modifying proteins, including DNA methylation proteins TET2, DNMT3A, and IDH...

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Detalhes bibliográficos
Publicado no:Hematol Oncol Clin North Am
Main Authors: Dunbar, Andrew, Park, Young, Levine, Ross
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927771/
https://ncbi.nlm.nih.gov/pubmed/33641866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hoc.2021.01.001
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