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Metabolic Vulnerabilities and Epigenetic Dysregulation in Myeloproliferative Neoplasms
The Janus kinase 2 (JAK2)-driven myeloproliferative neoplasms (MPNs) are associated with clonal myelopoiesis, elevated risk of death due to thrombotic complications, and transformation to acute myeloid leukemia (AML). JAK2 inhibitors improve the quality of life for MPN patients, but these approved t...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7734315/ https://ncbi.nlm.nih.gov/pubmed/33329600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.604142 |
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