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Recurring mutations in myeloproliferative neoplasms alter epigenetic regulation of gene expression

The prevalence of activating JAK2 mutations in myeloproliferative neoplasms (MPNs) suggests that aberrant gene expression due to deregulated signaling of the JAK2/STAT pathway plays an important role in the etiology of these diseases. While likely true, recent work has uncovered some fascinating new...

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Hlavní autor: Reuther, Gary W
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195930/
https://ncbi.nlm.nih.gov/pubmed/22016825
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