Impact of the CYP3A5, CYP3A4, COMT, IL-10 and POR Genetic Polymorphisms on Tacrolimus Metabolism in Chinese Renal Transplant Recipients

Tacrolimus is a widely used immunosuppressive drug for preventing the rejection of solid organ transplants. The efficacy of tacrolimus shows considerable variability, which might be related to genetic variation among recipients. We conducted a retrospective study of 240 Chinese renal transplant reci...

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Autori principali: Li, Chuan-Jiang, Li, Liang, Lin, Li, Jiang, Hai-Xia, Zhong, Ze-Yan, Li, Wei-Mo, Zhang, Yan-Jun, Zheng, Ping, Tan, Xu-Hui, Zhou, Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897654/
https://ncbi.nlm.nih.gov/pubmed/24465960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086206
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