IL-3 and CTLA4 gene polymorphisms may influence the tacrolimus dose requirement in Chinese kidney transplant recipients

The highly variable pharmacokinetics and narrow therapeutic window of tacrolimus (TAC) has hampered its clinical use. Genetic polymorphisms may contribute to the variable response, but the evidence is not compelling, and the explanation is unclear. In this study we attempted to find previously unkno...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Acta Pharmacol Sin
Prif Awduron: Liu, Mou-ze, He, Hai-yan, Zhang, Yue-li, Hu, Yong-fang, He, Fa-zhong, Luo, Jian-quan, Luo, Zhi-ying, Chen, Xiao-ping, Liu, Zhao-qian, Zhou, Hong-hao, Shao, Ming-jie, Ming, Ying-zi, Xin, Hua-wen, Zhang, Wei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342670/
https://ncbi.nlm.nih.gov/pubmed/28112181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.153
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