IL-3 and CTLA4 gene polymorphisms may influence the tacrolimus dose requirement in Chinese kidney transplant recipients

The highly variable pharmacokinetics and narrow therapeutic window of tacrolimus (TAC) has hampered its clinical use. Genetic polymorphisms may contribute to the variable response, but the evidence is not compelling, and the explanation is unclear. In this study we attempted to find previously unkno...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Liu, Mou-ze, He, Hai-yan, Zhang, Yue-li, Hu, Yong-fang, He, Fa-zhong, Luo, Jian-quan, Luo, Zhi-ying, Chen, Xiao-ping, Liu, Zhao-qian, Zhou, Hong-hao, Shao, Ming-jie, Ming, Ying-zi, Xin, Hua-wen, Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342670/
https://ncbi.nlm.nih.gov/pubmed/28112181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.153
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