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CYP3A5 polymorphisms in renal transplant recipients: influence on tacrolimus treatment
Tacrolimus is a commonly used immunosuppressant after kidney transplantation. It has a narrow therapeutic range and demonstrates wide interindividual variability in pharmacokinetics, leading to potential underimmunosuppression or toxicity. Genetic polymorphism in CYP3A5 enzyme expression contributes...
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| Publicat a: | Pharmgenomics Pers Med |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Dove Medical Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846312/ https://ncbi.nlm.nih.gov/pubmed/29563827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S107710 |
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