HIGH CHOLESTEROL-INDUCED NEUROINFLAMMATION AND AMYLOID PRECURSOR PROTEIN PROCESSING CORRELATE WITH LOSS OF WORKING MEMORY IN MICE

Recent findings suggest that hypercholesterolemia may contribute to the onset of Alzheimer’s disease (AD)-like dementia but the underlying mechanisms remain unknown. In this study, we evaluated the cognitive performance in rodent models of hypercholesterolemia in relation to neuroinflammatory change...

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Main Authors: Thirumangalakudi, Lakshmi, Prakasam, Annamalai, Zhang, Ran, Bimonte-Nelson, Heather, Sambamurti, Kumar, Kindy, Mark S., Bhat, Narayan R.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897170/
https://ncbi.nlm.nih.gov/pubmed/18410513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05415.x
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