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Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model
Down syndrome (DS) individuals develop several neuropathological hallmarks seen in Alzheimer's disease, including cognitive decline and the early loss of cholinergic markers in the basal forebrain. These deficits are replicated in the Ts65Dn mouse, which contains a partial trisomy of murine chr...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704550/ https://ncbi.nlm.nih.gov/pubmed/19135442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.11.021 |
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