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Obesity-Induced Insulin Resistance and Hyperglycemia: Etiological Factors and Molecular Mechanisms

Obesity is a major cause of type 2 diabetes, clinically evidenced as hyperglycemia. The altered glucose homeostasis is caused by faulty signal transduction via the insulin signaling proteins, which results in decreased glucose uptake by the muscle, altered lipogenesis, and increased glucose output b...

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Bibliographic Details
Main Authors: Jeevendra Martyn, J.A., Kaneki, Masao, Yasuhara, Shingo
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896971/
https://ncbi.nlm.nih.gov/pubmed/18580184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181799d45
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