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Kinetic and equilibrium studies of acrylonitrile binding to cytochrome c peroxidase and oxidation of acrylonitrile by cytochrome c peroxidase compound I

Ferric heme proteins bind weakly basic ligands and the binding affinity is often pH dependent due to protonation of the ligand as well as the protein. In an effort to find a small, neutral ligand without significant acid/base properties to probe ligand binding reactions in ferric heme proteins we we...

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Autors principals: Chinchilla, Diana, Kilheeney, Heather, Vitello, Lidia B., Erman, James E.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896955/
https://ncbi.nlm.nih.gov/pubmed/24291498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.11.084
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