Peroxygenase activity of cytochrome c peroxidase and three apolar distal heme pocket mutants: hydroxylation of 1-methoxynaphthalene

BACKGROUND: The cytochrome P450s are monooxygenases that insert oxygen functionalities into a wide variety of organic substrates with high selectivity. There is interest in developing efficient catalysts based on the “peroxide shunt” pathway in the cytochrome P450s, which uses H(2)O(2) in place of O...

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Autores principales: Erman, James E, Kilheeney, Heather, Bidwai, Anil K, Ayala, Caitlan E, Vitello, Lidia B
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733812/
https://ncbi.nlm.nih.gov/pubmed/23895311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-14-19
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