Oleanolic acid attenuates renal fibrosis in mice with unilateral ureteral obstruction via facilitating nuclear translocation of Nrf2

BACKGROUND: Renal interstitial fibrosis is a common final pathological process in the progression of kidney disease. This is primarily due to oxidative stress, which contributes to renal inflammation and fibrosis. Nuclear factor-erythroid-2-related factor 2 (Nrf2) is known to coordinate induction of...

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Autori principali: Chung, Sungjin, Yoon, Hye Eun, Kim, Soo Jeong, Kim, Sung Jun, Koh, Eun Sil, Hong, Yu Ah, Park, Cheol Whee, Chang, Yoon Sik, Shin, Seok Joon
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896758/
https://ncbi.nlm.nih.gov/pubmed/24393202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-7075-11-2
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