Fimasartan, a Novel Angiotensin-Receptor Blocker, Protects against Renal Inflammation and Fibrosis in Mice with Unilateral Ureteral Obstruction: the Possible Role of Nrf2

Objectives: A newly developed angiotensin II receptor blocker, fimasartan, is effective in lowering blood pressure through its action on the renin-angiotensin system. Renal interstitial fibrosis, believed to be due to oxidative injury, is an end-stage process in the progression of chronic kidney dis...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Med Sci
Hauptverfasser: Kim, Soojeong, Kim, Sung Jun, Yoon, Hye Eun, Chung, Sungjin, Choi, Bum Soon, Park, Cheol Whee, Shin, Seok Joon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643080/
https://ncbi.nlm.nih.gov/pubmed/26640409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.13187
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