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Fabry disease exacerbates renal interstitial fibrosis after unilateral ureteral obstruction via impaired autophagy and enhanced apoptosis

BACKGROUND: Fabry disease is a rare X-linked genetic lysosomal disorder caused by mutations in the GLA gene encoding alpha-galactosidase A. Despite some data showing that profibrotic and proinflammatory cytokines and oxidative stress could be involved in Fabry disease-related renal injury, the patho...

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Detalhes bibliográficos
Publicado no:Kidney Res Clin Pract
Main Authors: Chung, Sungjin, Son, Mina, Chae, Yura, Oh, Songhee, Koh, Eun Sil, Kim, Yong Kyun, Shin, Seok Joon, Park, Cheol Whee, Jung, Sung-Chul, Kim, Ho-Shik
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Nephrology 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237117/
https://ncbi.nlm.nih.gov/pubmed/34024086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.23876/j.krcp.20.264
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