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A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury

BACKGROUND: Many diseases and pathological conditions are characterized by transient or constitutive overproduction of reactive oxygen species (ROS). ROS are causal for ischemia/reperfusion (IR)-associated tissue injury (IRI), a major contributor to organ dysfunction or failure. Preventing IRI with...

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Autors principals: Ashraf, Muhammad Imtiaz, Ebner, Matthias, Wallner, Christoph, Haller, Martina, Khalid, Sana, Schwelberger, Hubert, Koziel, Katarzyna, Enthammer, Marion, Hermann, Martin, Sickinger, Stephan, Soleiman, Afschin, Steger, Christina, Vallant, Stephanie, Sucher, Robert, Brandacher, Gerald, Santer, Peter, Dragun, Duska, Troppmair, Jakob
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896752/
https://ncbi.nlm.nih.gov/pubmed/24423080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-12-6
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