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asymptoticMK: A Web-Based Tool for the Asymptotic McDonald–Kreitman Test

The McDonald–Kreitman (MK) test is a widely used method for quantifying the role of positive selection in molecular evolution. One key shortcoming of this test lies in its sensitivity to the presence of slightly deleterious mutations, which can severely bias its estimates. An asymptotic version of t...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Haller, Benjamin C., Messer, Philipp W.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427504/
https://ncbi.nlm.nih.gov/pubmed/28341700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.039693
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