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Controlling Type-I Error of the McDonald–Kreitman Test in Genomewide Scans for Selection on Noncoding DNA
Departures from the assumption of homogenously interdigitated neutral and putatively selected sites in the McDonald–Kreitman test can lead to false rejections of the neutral model in the presence of intermediate levels of recombination. This problem is exacerbated by small sample sizes, nonequilibri...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581974/ https://ncbi.nlm.nih.gov/pubmed/18791238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.091850 |
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