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Controlling Type-I Error of the McDonald–Kreitman Test in Genomewide Scans for Selection on Noncoding DNA

Departures from the assumption of homogenously interdigitated neutral and putatively selected sites in the McDonald–Kreitman test can lead to false rejections of the neutral model in the presence of intermediate levels of recombination. This problem is exacerbated by small sample sizes, nonequilibri...

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Bibliographische Detailangaben
1. Verfasser: Andolfatto, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581974/
https://ncbi.nlm.nih.gov/pubmed/18791238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.091850
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