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A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury
BACKGROUND: Many diseases and pathological conditions are characterized by transient or constitutive overproduction of reactive oxygen species (ROS). ROS are causal for ischemia/reperfusion (IR)-associated tissue injury (IRI), a major contributor to organ dysfunction or failure. Preventing IRI with...
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Main Authors: | , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896752/ https://ncbi.nlm.nih.gov/pubmed/24423080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-12-6 |
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