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Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers

BACKGROUND: This study was conducted to compare the oral bioavailability of an itopride extended-release (ER) formulation with that of the reference immediate-release (IR) formulation in the fasting state. The effect of food on the bioavailability of itopride ER was also assessed. METHODS: A single-...

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Main Authors: Yoon, Seonghae, Lee, Howard, Kim, Tae-Eun, Lee, SeungHwan, Chee, Dong-Hyun, Cho, Joo-Youn, Yu, Kyung-Sang, Jang, In-Jin
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896282/
https://ncbi.nlm.nih.gov/pubmed/24470753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S53027
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