Evaluation of the effects of food on levodropropizine controlled-release tablet and its pharmacokinetic profile in comparison to that of immediate-release tablet

BACKGROUND: Levodropropizine is a non-opioid antitussive agent that inhibits cough reflex by reducing the release of sensory peptide in the peripheral region. To improve patients’ compliance, a controlled-release (CR) tablet is under development. The aim of this study was to compare the pharmacokine...

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發表在:Drug Des Devel Ther
Main Authors: Lee, Soyoung, Nam, Kyu-Yeol, Oh, Jaeseong, Lee, SeungHwan, Cho, Sang-Min, Choi, Youn-Woong, Cho, Joo-Youn, Lee, Beom-Jin, Hong, Jang Hee
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2018
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973308/
https://ncbi.nlm.nih.gov/pubmed/29872264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S146958
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