Immediate release tablet formulation of varenicline salicylate and comparative pharmacokinetic study in human volunteers

PURPOSE: To develop an immediate release-type tablet containing varenicline salicylate (VRC-S), a smoking cessation agent, formulation and stability studies were performed. The in vitro dissolution and in vivo pharmacokinetic (PK) behavior of the tablets were compared with those of the commercial pr...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Kwak, Seong Shin, Lee, Eun Seok, Yoon, Ho Yub, Kim, Chang Hyun, Goo, Yoon Tae, Kang, Myung Joo, Lee, Sangkil, Lee, Bong Sang, Jeon, Hong Ryeol, Oh, Chang Hyun, Choi, Young Wook
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186768/
https://ncbi.nlm.nih.gov/pubmed/30349192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S178456
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