Immediate release tablet formulation of varenicline salicylate and comparative pharmacokinetic study in human volunteers

PURPOSE: To develop an immediate release-type tablet containing varenicline salicylate (VRC-S), a smoking cessation agent, formulation and stability studies were performed. The in vitro dissolution and in vivo pharmacokinetic (PK) behavior of the tablets were compared with those of the commercial pr...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Kwak, Seong Shin, Lee, Eun Seok, Yoon, Ho Yub, Kim, Chang Hyun, Goo, Yoon Tae, Kang, Myung Joo, Lee, Sangkil, Lee, Bong Sang, Jeon, Hong Ryeol, Oh, Chang Hyun, Choi, Young Wook
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186768/
https://ncbi.nlm.nih.gov/pubmed/30349192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S178456
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