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ROR1 can interact with TCL1 and enhance leukemogenesis in Eµ-TCL1 transgenic mice
Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is an oncoembryonic antigen found on chronic lymphocytic leukemia (CLL) B cells, but not on normal adult tissues. We generated transgenic (Tg) mice with human ROR1 regulated by the murine Ig promoter/enhancer. In contrast to nontransgenic litter...
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| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896194/ https://ncbi.nlm.nih.gov/pubmed/24379361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308374111 |
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