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Hydrophobic plug functions as a gate in voltage-gated proton channels

Voltage-gated proton (Hv1) channels play important roles in the respiratory burst, in pH regulation, in spermatozoa, in apoptosis, and in cancer metastasis. Unlike other voltage-gated cation channels, the Hv1 channel lacks a centrally located pore formed by the assembly of subunits. Instead, the pro...

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Hlavní autoři: Chamberlin, Adam, Qiu, Feng, Rebolledo, Santiago, Wang, Yibo, Noskov, Sergei Y., Larsson, H. Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896152/
https://ncbi.nlm.nih.gov/pubmed/24379371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318018111
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