Chargement en cours...
Hydrophobic gasket mutation produces gating pore currents in closed human voltage-gated proton channels
The hydrophobic gasket (HG), a ring of hydrophobic amino acids in the voltage-sensing domain of most voltage-gated ion channels, forms a constriction between internal and external aqueous vestibules. Cationic Arg or Lys side chains lining the S4 helix move through this “gating pore” when the channel...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
|---|---|
| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2019
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6754559/ https://ncbi.nlm.nih.gov/pubmed/31462498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905462116 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|